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03/11/2016 (Added to site)
Author(s): Impellizeri, J.; Aurisicchi, L.; Forde, P.; Soden, D. M.

Electroporation in veterinary oncology

Journal: The Veterinary Journal, 217 (2016), pp. 18-25
DOI: 10.1016/j.tvjl.2016.05.015
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Abstract: Cancer treatments in veterinary medicine continue to evolve beyond the established standard therapies of surgery, chemotherapy and radiation therapy. New technologies in cancer therapy include a targeted mechanism to open the cell membrane based on electroporation, driving therapeutic agents, such as chemotherapy (electro-chemotherapy), for local control of cancer, or delivery of gene-based products (electro-gene therapy), directly into the cancer cell to achieve systemic control. This review examines electrochemotherapy and electro-gene therapy in veterinary medicine and considers future directions and applications.



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