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11/10/2012 (Added to site)
Author(s): Kotnik, T.; Kramar, P.; Pucihar, G.; Miklavčič, D.; Tarek, M.

Cell Membrane Electroporation — Part 1: The Phenomenon

Journal: IEEE Electrical Insulation Magazine, 28/5 (2012), pp. 14-23
DOI: 10.1109/MEI.2012.6268438
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Introduction: Each biological cell, trillions of which build our bodies, is enveloped by its plasma membrane. Composed largely of a bilayer (double layer) of lipids just two molecules thick (about 5 nm), and behaving partly as a liquid and partly as a gel, the cell
plasma membrane nonetheless separates and protects the cell from its surrounding environment very reliably and stably. Embedded within the lipid bilayer, also quite stably, are a number of different proteins, some of which act as channels and pumps,
providing a pathway for transporting specific molecules across the membrane. Without these proteins, the membrane would be a largely impenetrable barrier.



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