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01/02/2013 (Added to site)
Author(s): Nikolova, B.; Georgieva, M.; Savu, D.; Tsoneva, I.

Cell Membrane Alteration by Weak Alternating Electric Field at Low Frequency

Journal: Romanian Reports in Physics, 64/4 (2012), pp. 1046-1052
DOI: /
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Abstract: The aim is to estimate the influence of sinusoidal (ac) field in combination with the cytostatic drug gemcitabine on the therapeutic effect of malignant cells. Electrotreatment is cell line dependent. There is threshold frequency window (1Hz) that is the most suitable for drug delivery. Hematopoietic cells are more sensitive to the electrotreatment as compared with human lymphocytes from healthy donors.


Keywords: drug delivery    electrotreatment    gemcitabine   

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