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25/11/2012 (Added to site)
Author(s): Mezeme, M. E.; Kranjc, M.; Bajd, F.; Sersa, C.; Brosseau, C.

Assessing how electroporation affects the effective conductivity tensor of biological tissues

Journal: Applied Physics Letters, 101/213702 (2012), pp. 1-5
DOI: 10.1063/1.4767450
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Abstract: We report calculations of the anisotropy ratio of the electrical conductivity of a simple model of a loose connective biological tissue described as a random assembly of multiscale undeformable core-shell and controlled polydisperse spherical structures. One can estimate a 10% increase in the anisotropy ratio due to the application of electric field (duration 100 μs) above the electroporation threshold (40 kV m-1) up to 120 kV m-1. These findings are consistent with the experimental data on the field-induced anisotropy dependence of the electrical conductivity due to cell membrane electroporation.


Keywords: electroporation    modelling    tissue   

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