print small

Participating Countries:

Algeria

Argentina

Australia

Austria

Belgium

Bosnia and Herzegovina

Bulgaria

Croatia

Czech Republic

Denmark

Finland

France

FYR of Macedonia

Germany

Greece

Iceland

Ireland

Israel

Italy

Lithuania

Morocco

Netherlands

New Zealand

Poland

Portugal

Romania

Russian Federation

Serbia

Slovenia

Spain

Sweden

Switzerland

Turkey

Ukraine

United Kingdom

United States

Member area provided by LTFE
COST is supported by the EU Framework Programme Horizon 2020
This website is supported by COST
06/02/2015 (Added to site)
Author(s): Jiang, C.; Davalos, R.; Bischof, J.

A Review of Basic to Clinical Studies of Irreversible Electroporation Therapy

Journal: IEEE Transactions on Biomedical Engineering, 62/1 (2015), pp. 4-20
DOI: 10.1109/TBME.2014.2367543
Request reprint  |  Tell your friend  | 

Abstract: The use of Irreversible Electroporation (IRE) for cancer treatment has increased sharply over the past decade. As a non-thermal therapy, IRE offers several potential benefits over other focal therapies which include: (1) short treatment delivery time, (2) reduced collateral thermal injury, and (3) the ability to treat tumors adjacent to major blood vessels. These advantages have stimulated widespread interest in basic through clinical studies of IRE. For instance, many in vitro and in vivo studies now identify treatment planning protocols (IRE threshold, pulse parameters, etc.), electrode delivery (electrode design, placement, intra-operative imaging methods, etc.), injury evaluation (methods and timing), and treatment efficacy in different cancer models. Therefore, this work reviews the in vitro, translational, and clinical studies of IRE cancer therapy based on major experimental studies particularly within the past decade. Further, this work provides organized data and facts to assist further research, optimization, and clinical applications of IRE.



Project Office

Working groups

Steering Committee

Founding members

DC Rapporteurs

Related sites: